NEUR 8385 - Systems Biology

3 Credit Hours
Prerequisites: Grade of C or higher in MATH 6010 or MATH 6275.
Description
This course provides an introduction to systems biology from mathematical modeling point of view. It will introduce biology students to mathematical modeling, and mathematical students to systems biology. Biological topics will include gene systems, protein systems, metabolic systems and signaling systems. Mathematical tools will include basic modeling concepts, approximation, static networks, linear vs. nonlinear systems and how to linearize nonlinear systems, and parameter estimation and optimization. Specific case studies will include integrative analysis of genome, protein, and metabolite data, systems biology in medicine and drug development, and synthetic biology.